Phytochemicals, α-glucosidase and α-amylase Inhibitory Efficiency of Brittle Wort (Chara corallina) Extract

This research is the first to evaluate brittle wort (Chara corallina) extract for phytochemical content and inhibitory effects against a-glucosidase a-amylase activities. An ethanolic of C. corallina had strongest enzyme effect. The inhibition efficiencies all extracts were more potent than those a-glucosidase, with IC50 values 8.43±0.18 mg/mL 1.78±0.07 a-amylase. Inhibition efficiency was related total phenolic content, DPPH radical scavenging activity, ATBS activity metal-chelation extracts. Phytochemical screening demonstrated presence triterpenoid β-sitosterol. These findings provide useful supporting data further applications extract.